Synthetic biology
Understanding and optimising synthetic biological systems
Synthetic biology explores the design and construction of biological components, both for understanding life’s fundamental principles and applying them in biotechnology. Within this domain, our group is currently engaged in two areas:
Cell-free protein expression
We develop and analyse computational models to probe conditions that drive self-regeneration within cell-free expression systems. We aim to both improve the efficiency and sustainability of protein production and gain deeper insights into hallmarks of self-regeneration underpinning living systems.
Model inference and optimal experimental design
We develop robust methods for parameter inference and optimal experimental design. These tools allow us to propose experiments designed to maximise the insights derived and expedite the design-build-test-learn cycle.